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224 Recent studies have further shown that some mutations in RNF43, such as p.G659fs, do not affect -catenin signal transduction, while the C-terminal truncated mutant has a WNT signal transduction function similar to that of wild-type RNF43

After two weeks, when behaviorally assessed, only the 600 g NPY (double effective dose in males) or combined 600 g NPY with protease inhibitor prevented SPS impairments and depressive-like behavior, indicative of sexually-divergent effects and the role of NPY in the CRH/NPY pathway and HPA axis regulation [134]
53(4): p
Biomacromolecules 22 , 26252640 (2021)