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This accompanied reduced inflammatory markers and decreased levels of elastin-degrading enzymes that impair healing
In various conditions with mitochondrial impairment, such cellular energy deficits have been associated with symptoms like fatigue and pain (Sui et al., 2013
Although many of the symptoms of ME/CFS overlap with other diseases, one feature that sets ME/CFS apart is a worsening of symptoms in response to relatively minor physical, cognitive, orthostatic or even emotional exertion (13)
The recent development of more complex therapies and the extension of interest in the domain of senescence in different fields of research allow to extend the possibility to discover powerful therapies
