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This pathway primarily occurs in the liver and kidney and involves four key enzymes: Trimethyllysine Hydroxylase (TMLH), Hydroxytrimethyllysine Aldolase (HTMLA), Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH), and -Butyrobetaine Hydroxylase (BBOX)

Tissues characterized by fast replicating cells also show reduced protein synthesis
