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This review synthesizes current insights into the mechanisms underlying residual symptoms in HT and critically evaluates contemporary and emerging therapeutic approaches aimed at improving patient-reported outcomes and long-term disease management 1 Introduction Hypothyroidism is a common endocrine disorder characterized by insufficient thyroid hormone production, estimated to affect a range of 4.825.8% of women and 0.97.9% of men in the general population, with a variable prevalence due to different definitions used and the population studied (13)

The higher ROS concentration, the greater the bactericidal efficiency of aminoglycosides and -lactams 66,73

ROS influence proteasomal, lysosomal, and mitochondrial function, which, in turn, regulate the cellular response to oxidative damage (Schapira et al., 2014)

Often used when treating mold toxicity and biotoxin illness