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Subsequently OAA is reduced to malate (MAL), with concomitant oxidation of NADH to NAD +

High Serine and Glycine Utilization in Cancer In addition to methionine addiction, the elevated consumption of serine and glycine was also noted across the NCI-60 human tumor cell lines [96]

It is located on the outer membrane of the mitochondria inside the cell and forms dimers (Denney and Denney 1985
