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55 In an in vitro A549 model infected with influenza (strains A and B), N-acetylcysteine was shown to inhibit expression and release of MUC5AC, IL6, and TNF-, reduce intracellular hydrogen peroxide level, restore intracellular pool of total thiols, diminish NF-B translocation to the cell nucleus, attenuate activation of mitogen activated protein kinase p38, and prevent replication of the viruses

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Numerous studies have highlighted the relationship between disease progression and markers of neuroinflammation [162]