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If the B12 deficiency is caused specifically by pernicious anemia, the patient may develop stomach cancer, birth defects such as spina bifida, anencephaly, or encephalocele [10]
[DOI] [PubMed] [Google Scholar] 96.Bencardino S., DAmico F., Faggiani I., Bernardi F., Allocca M., Furfaro F., Parigi T.L., Zilli A., Fiorino G., Peyrin-Biroulet L., et al

Given in vitro efficacy and lack of cytotoxicity of GSH-MEE, the researchers suggested the development of GSH-MEE, instead of GSH, as an efficacious and safe molecule for the treatment of hyperpigmentation [22]