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the pathogen-induced ROS production includes direct production by pathogens where many pathogens, such as bacteria and viruses, may generate ROS directly during their metabolic activities, consequently this causes activation of the host's immunological response, specifically neutrophils, and macrophages

This process facilitates the efficient clearance of NETs and their associated microorganisms, effectively curbing excessive inflammation and mitigating potential tissue damage

SanzCuesta T, GonzlezEscobar P, RiesgoFuertes R, GarridoElustondo S, CuraGonzlez I, MartnFernndez J, et al

Edited by Boris Zhivotovsky Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made