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Description
Prior to entering the nucleus, conjugation of the activated cisplatin with glutathione (GSH) by GSH S -transferases (GSTs) ( C ), or interaction with the sulfhydryl-containing metallothioneins ( D ) can result in reduced drug efficacy
Similarly, MALAT1 knockdown reduced PAK2 protein levels, which were reversed upon miR-155-5p inhibition (Figure 4A,C)
Response to Comments Because of the large number of public comments we normally receive on Federal Register documents, we are not able to acknowledge or respond to them individually
110 Hydrogels also serve as delivery carriers for various therapeutic agents
