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The landmark Phase IIb clinical trial published in The Lancet (TIPO-1 study) evaluated 203 obese patients randomly assigned to receive tesofensine at doses of 0.25mg, 0.5mg, or 1.0mg daily for 24 weeks alongside an energy-restricted diet

ERK plays important roles in the processes involving cell growth, cell proliferation, and cell survival (Lavoie et al

Thomas SN, Funk KE, Wan Y, Liao Z, Davies P, Kuret J, Yang AJ
