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Since peptides' oral bioavailability is usually limited, they are often administered by injection into subcutaneous fat (as around the belly, thighs, or upper arms).24 TB4 or TB-500 injections are typically administered once per day, at any time of day, five days per week

At the same time, HCY accumulates in the blood, leading to hyperhomocysteinemia

J Trace Elem Med Biol 48:172180

Reviewing solvent compatibility, pH, handling procedures, and storage conditions often resolves the issue
