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Some aggressive protocols might explore up to 1% or even slightly higher, but this requires careful monitoring

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Studies in both animals and humans suggest DSIP modulates endogenous opioid peptide levels, stabilizing the beta-endorphin fluctuations that contribute to withdrawal symptoms (Dick et al., Eur J Pharmacol, 1984

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doi: 10.3892/ijo.2018.4380

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M., Vindry, C., Ohlmann, T., & Chavatte, L

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