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FoxO3 regulates neural stem cell homeostasis

This process is crucial for maintaining the integrity of cell membranes

As tirzepatide clears over 3-4 weeks, gastrointestinal symptoms typically improve gradually, appetite may return, and blood glucose levels may rise in patients with diabetes

Data and code availability The code generated during this study is available at METHOD DETAILS Hepatocyte specific model Starting with the thermodynamically curated human genome-scale Recon 3D 31,32 , we reconstructed a hepatocyte metabolic model by taking into account the physiology of hepatocytes and the genes expressed in liver cells