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doi: 10.1016/j.fsi.2019.10.047
Ma et al., 2023)
The progressive loss of nephrons reduces renal 1-hydroxylase activity, limiting the production of active 1,25-dihydroxyvitamin D (1,25(OH)D), whereas urinary loss of vitamin D-binding protein (VDBP) due to proteinuria further exacerbates 25(OH)D deficiency (3)
In this study, AST administration significantly improved learning and memory performance while attenuating hippocampal oxidative damage and inflammatory responses
