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Nonpharmacologic treatment options with published evidence of efficacy in patients with CIPN include chemotherapy dose reduction, discontinuation of the offending chemotherapeutic agent(s), acupuncture, avoiding cold temperatures/maintaining warmth, physical activity, and massaging affected areas ( TABLE 3 )

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As can be seen in Figure 8A, none of these three amino acids showed infrared absorption peaks at 1,654 cm 1