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Abstract 2289 Richardson P, Harrison S, Facon T, Yong K, Raje N, Alegre A et al 2020 Isatuximab plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma patients with 1q21 gain: insights from phase 1 and phase 3 studies

In addition to limited absorption via the IF, the intake of high-dose supplements leads to passive diffusion, i.e., the vitamin can freely enter the bloodstream without IF binding and receptor uptake

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Evidence Boundary Included here only to clarify the evidence gap