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A majority of the included studies assessed PLC versus placebo (11 studies, 1395 participants), and one study assessed propionyl L-carnitine (PLC) versus L-carnitine (one study, 26 participants)

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All data were analyzed using R software version 3.43, JMP version 14, or Prism (GraphPad Software)

On the other hand, some literature suggests that L-carnitine, by promoting pyruvate oxidation, may accelerate carbohydrate breakdown, leading to rapid depletion of muscle glycogen and potentially producing a detrimental effect on exercise performance
