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In PRCA, CEBPB recruits DNA methyltransferases to epigenetically silence ER, facilitating proliferation and apoptosis resistance [77] CEBPB, as a key epigenetic regulator in ovarian cancer chemoresistance, recruits DOT1L to mediate H3K79 methylation, maintain open chromatin at drug-resistance genes [112]
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Plots of ln k (where k is the experimentally determined initial rate) versus 1/ T were calculated from the solvent-free liquid [C-RML][ S 1 ]/pNPPal assay rate data and showed a linear response (Fig
