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Ferroptosis suppressor protein 1 (FSP 1 ), a flavoprotein oxidoreductase, may determine the role of CoQ 10 in apoptosis and ferroptosis, and its pro-apoptotic function may be achieved through the inhibition of redox activity ( 1 , originally named apoptosis-inducing factor mitochondrial associated 2 (AIFM 2 ), is also a mitochondrial pro-apoptotic protein ( 1 is able to use NADPH to regenerate lipophilic radicals to trap antioxidant