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[DOI] [PMC free article] [PubMed] [Google Scholar] 112.Sellmann C., Jin C.J., Degen C., De Bandt J.P., Bergheim I

Core safety evaluations typically encompass strain identification and characterization, pathogenicity and toxicity assessment, and contaminant screening ( Within the United States, probiotic regulation falls under the authority of the FDA, which generally classifies these products as dietary supplements or food ingredients in accordance with the Dietary Supplement Health and Education Act (DSHEA) of 1994 (566)

For instance, in an investigation of atherosclerosis induced by HUA, exposure to sUA significantly heightened macrophage iron death through the NRF2/SLC7A11/Glutathione peroxidase 4 (GPX4) signaling pathway (67)