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Western blot and statistical analysis of the protein expression level of 4-HNE were consistent with the immunostaining results (Figure 6C)

Polymeric nanoparticles, such as those generated from polylactic-co-glycolic acid (PLGA) or polyethylenimine (PEI), also appear promising, as these materials can be tailored to deliver siRNA precisely to microglia or neurons while allowing for prolonged release (96)

Studies have shown that patients with cystic fibrosis frequently exhibit dysregulated iron metabolism, with aberrant iron accumulation creating a favorable environment for microbial pathogens-particularly P

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