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Description
Magnesium deficiency causes glutathione loss and increases dramatically free-radical production
Plasticity is controlled by levels of -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and n-methyl-d-aspartate (NMDA) receptors
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Consequently, systemic oxidative burden may decrease circulating PON1 activity and amplify lipid peroxidation, creating a self-reinforcing cycle that contributes to the pathophysiology of sarcoidosis
