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For skin whitening, 8-10 sessions are generally needed, with specific intervals between treatments

Thus, combined activation of PPAR and PPAR may cause cardiac toxicity due to elevated toxic lipid species

This SOD1-mediated ERAD impairment induces further ER stress, upregulates zinc transporters and suppresses protein synthesis, positioning SOD1 as a molecular sensor that links zinc status to ER proteostasis failure
