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2,3 Dwarfism can result from a mutation in the hepatic GH receptor which yields insensitivity to secreted GH

The most widely used system for conditional knockout (gene inactivation) is the Cre-lox system (4-6)

Its primary role is to protect cells from oxidative stressa process where unstable molecules called free radicals cause damage to cellular structures

The other two adducts, 2,3-dihydro-2-(N-formyl-2,3,6-triamino-4-oxopyrimidine-N-yl)-3-hydroxy AFB 1 and 8,9-dihydro-8-(2-amino-6-formamide-4-oxo-3,4-dihydropyrimid-5-yl formamido)-9-hydroxy AFB 1 (AFB 1 -FAPY and AFB 1 III respectively) are not spontaneously but appear to be removed catalytically by DNA repair enzymes