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An age-dependent decline in MUNE and CMAP amplitude occurs in both SMA 1 and 2, and significant progressive denervation may be present before the onset of symptoms [111, 119]
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
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Dalton LM, N Fhloinn DM, Gaydadzhieva GT, Mazurkiewicz OM, Leeson H, Wright CP
