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Elevated homocysteine has been associated with many conditions including neural tube defects, Impaired childhood cognition (autism), macular degeneration, stroke, depression and anxiety (Chung etal, 2017) and cognitive impairment in the elderly

Oncotarget 6(10):73657378 Kourelis TV, Siegel RD (2012) Metformin and cancer: new applications for an old drug

Asia Pac J Clin Nutr 10, 128133

In the UK, B12 injectionstypically hydroxocobalaminare prescribed through the NHS for documented deficiency states such as pernicious anaemia or malabsorption disorders
