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Reduction in expression levels of host factors was correlated with reduced virus infectivity of human epithelial lung cells in a cell-culture model

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We showed that inherent anxiety at baseline and elevated expression of the mineralocorticoid receptors (MR) in the hippocampus predisposes to a stress-induced suppression of expression of metabotropic glutamate receptors-2 (mGlu2, a key inhibitor of spontaneous glutamate release) with development of depressive-like behavior via epigenetic mechanisms of histone acetylation [20]

doi:10.1007/s40256-019-00384-y Alehagen U, Aaseth J, Alexander J, Johansson P