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Systemic PCD is associated with many adverse clinical findings, including, but not limited to, hepatomegaly, muscle weakness, elevated transaminase levels, hyperammonemia, and altered gastrointestinal motility [59]

For example, since age, lifestyle, medication, geography, and diet are all able to impact microbiome function and composition (583585), detailed descriptions of food consumption at least 48 hours before the sample collection should be included

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