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Description
When NNMT is inhibited by compounds like 5-Amino-1MQ, more nicotinamide becomes available for conversion to NAD+ via NAMPT
Here we determine that FUS/TLS directly binds the SMN protein, with its association mediated by the RGG motifs in FUS/TLS and the Tudor domain in SMN
In ADCD, the unrestricted degradation of cellular contents leads to a disrupted cellular environment
[DOI] [PMC free article] [PubMed] [Google Scholar] Shi, C
