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Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis

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The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

34 However, in a placebo-controlled trial in 99 subjects with PCOS, 12 weeks of treatment with a synbiotic supplement providing the prebiotic inulin plus a combination of seven probiotic strains improved LDL- and high-density lipoprotein (HDL)-cholesterol levels, but did not alter triglyceride levels, body weight, or body composition
