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2017, J Pharm Sci), but standard topical creams deliver limited concentrations
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The high-affinity nature of the transport mechanism was demonstrated by Iversen and Neal (61) also using brain slices and this study showed GABA uptake in both neurons and astrocytes
Glutamine antagonists/analogues Glutamine antagonists/analogues including 6-diazo-5-oxo-norleucine (DON), acivicin, and JHU-083, are substances that are highly similar to glutamine in structure and capable of selectively blocking multiple metabolic reactions in which glutamine is involved
