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Finally, while PPAR activation is considered necessary and sufficient for adipogenesis in humans and cell culture systems, including mouse models and cell lines such as 3T3-L1, the fundamental mechanisms of adipogenesis are highly conserved across species, including humans
This lipid-centric repair strategy echoes the lipid storm observed post-stroke, where dysregulated lipid signaling wreaks havoc
The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes
