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Description
Treatment with intranasal cyanocobalamin should be delayed until symptoms resolve in patients with nasal congestion, allergic rhinitis, and upper respiratory infection
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Hydroxocobalamin is a more stable form of B12 but it first needs to be converted to an active form before use in metabolism.
Dose-response relationships appear to be tissue-specific, with adipose tissue showing high sensitivity while other tissues may require higher concentrations for detectable effects
