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Given its immunoregulatory functions, the complement system unsurprisingly is involved in cuprizone-induced demyelination

10.1179/016164101101198659 [DOI] [PubMed] [Google Scholar] Tsuzuki N., Miyazawa T., Matsumoto K., Nakamura T., Shima K., Chigasaki H

apoE / mice were treated with low- or high dose exendin-4GLP-1 receptor agonist ( ) and MCP-1inflammatory and atherogenic mediators

GCLC can be cleaved by a caspase 3-dependent mechanism from the full-length 73 kDa to a 60 kDa form during apoptosis induced by TGF-1, TNF and -Fas [45,130]
