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Serious reactions are uncommon, and Dr

Instituto Nacional de Diabetes y Enfermedades Digestivas y Renales National Institute of Diabetes and Digestive and Kidney Diseases

These include cognitive problems, chronic pain, sensory hypersensitivity, and issues with sleep

Of these 50 semaglutide-treated patients that developed anti-semaglutide antibodies, 28 patients (1.6% of the overall population) developed antibodies cross-reacting with native GLP-1.The in vitro neutralizing activity of the antibodies is uncertain at this time