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It increases matrix remodeling and angiogenesis in healing tissues

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Our scRNA-seq data further support this, showing hepatic-like markers enriched in a separate multilineage cluster while SC- clusters in KO cells exhibit transcriptional profiles similar, yet not identical, to WT

Erythrocytes affect hemostasis and thrombosis by altering blood viscosity, blood flow dynamics, secreting RBC-derived microvesicles, interactions with platelets or endothelial cells, fibrinogen-induced RBC aggregation, activation of blood coagulation factors, direct modulation of thrombin and fibrin formation, or formation of polyhedral-like erythrocytes in thrombi [47,48,49]