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Altogether, by enabling the TCA cycle, Fe-S clusters take part in the controlled combustion of nutrients and supply metabolic precursors for nucleotide, lipid, and protein biogenesis

83 , 84 These genes are in part activated by forkhead transcription factor (FoxO1), a critical transcription factor whose deacetylation and activation are mediated by TH

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Therefore, dietary interventions aimed at prevention and treatment of CVD should emphasize a balanced intake of specific amino acids
