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Humans are also exposed to heavy metals through industrial operations such as foundries, smelters, oil refineries, petrochemical plants, pesticide manufacturing, and the chemical industry (Mitra et al

Besides the L-galactose pathway, the D-galacturonate pathway is also reported to be the major pathway for AsA biosynthesis in plants, in which GALUR is a crucial enzyme ( FaGALUR gene ectopically, AsA content was increased ( AdGALUR expression in kiwifruit ( PpGALUR in the early stage of storage but considerably increased expression was observed at the end of storage

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NAC is a well-studied, Food and Drug Administration (FDA)-approved drug, with a favorable safety profile in neonates, giving these findings significant translational potential in the face of the opioid epidemic and rising rates of NAS after exposure to opioids in utero
