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The combination of the grinding action of the antrum, the retropulsion, and the squeezing of the chime through the pyloric sphincter into the duodenum is required for the emulsification of dietary fat and this plays an important role in the overall digestion and absorption of fat

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Altogether, the dysbalanced regulation of mitochondrial and cytosolic Ca 2+ cycling contributes to ASD pathogenesis by causing mitochondrial dysfunction, cell signaling breakdown, cytotoxicity, and oxidative stress