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(Travis et al., 2015) Fusion gene strategies can be employed to co-express helper epitopes or cytokines (e.g., GM-CSF, IL-12) along with tumor antigens, thereby promoting T-helper memory cell differentiation and sustaining long-term immune responses (van der Burg et al., 2016)
This direct delivery method is particularly beneficial for individuals with conditions that affect nutrient absorption, such as Crohns disease or pernicious anemia
Semeere AS, Nakanjako D, Ddungu H, et al
such patients with regular and chronic ethanol consumption be monitored for the desired therapeutic response to vitamin B12
