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Data analysis Substrate depletion was determined by the quantitative differences between the metabolism samples and the corresponding zero-time samples

Researchers induced knee osteoarthritis in rabbits using collagenase injections, then treated the animals with weekly intra-articular injections of AOD-9604, hyaluronic acid, or a combination of both compounds

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In some cases, further work needs to happen to find and address the root cause(s) that are contributing to the condition, such as infections , traumatic stress, and toxins