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Previous studies have shown that in bone marrow stromal cells (BMSCs), production of HGF results in the production of IL-11, IL-10, IL-6, IL-8, stromal cell-derived factor (SDF)-1, and vascular endothelial growth factor (VEGF) [43]

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A peer-reviewed overview in the International Journal of Molecular Sciences (Araj et al., Medical University of Warsaw, 2025) establishing Epithalon as a highly bioactive pineal tetrapeptide with documented mechanisms spanning telomere maintenance, epigenetic regulation, antioxidant defense, immune recalibration, and circadian rhythm restoration provides the scientific framework for all five mechanisms described in this section

Discovery and development of novel melanogenic drugs