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Another function of Tau is revealed by its presence in the nucleus, where it has been reported to play roles in heterochromatin organization and chromatin stability by binding and interaction with heterochromatin, as well as modifying the liquidliquid phase separation (LLPS) characteristic of chromatin components (Abasi et al., 2024)

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Outcomes measures Primary PK endpoints were the area under the serum concentration-time curve from time 0 to the last measurable concentration time point after drug administration (AUC 0-t ) and the maximum serum concentration (C max )