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Inhibition of neuronal glutamine transporters resulted in decreased levels of Glu-Gln in the mPFC and manifested depressive-like behaviors [14], and a reduction of their expression was observed in CIS-induced depressive mice [18]

rhamnosus , have been associated with alleviating psychological distress, reducing anxiety symptoms, and improving behaviors characteristic of ASD, respectively

10.1111/j.1743-6109.2012.02741.x 263

Among these, histone modifications like ubiquitination and DNA methylation are important mechanisms regulating gene transcriptional status
