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PMID: 26690419

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Testing of MMA has additional value in identifying patients with clinically relevant metabolic deficiency when vitamin B12 is below 304 pmol/L (412 pg/mL) (271)

Some users run 8-12 week injectable courses and bridge with oral precursors (NAC or liposomal glutathione) during off periods, though this appears to be a cost management strategy rather than a physiological requirement
