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2022, doi:10.1371/journal.pone.0273186 Georgakopoulou, Vasiliki Epameinondas et al

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Binding to antioxidant response elements (AREs) induces the transcription of genes regulated by AREs, which initiates the expression of genes encoding cytoprotective enzymes, such as antioxidative stress proteins, especially antioxidant enzymes ( Figure 2 The antioxidant response is also modulated by signaling pathways mediated by adenosine 5'-monophosphate-activated protein kinase (AMPK)

RTs Three Key Takeaways: Improved Respiratory Symptoms Benralizumab significantly reduced symptoms such as cough, wheeze, and breathlessness within 28 days of treatment