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Clinically, cagrilintide is being studied for weight management, but research-use cagrilintide is not an approved weight-loss drug

In the third pathway, however, the NAPQI intermediate is toxic when GSH is depleted by an overdose of acetaminophen

The Xc complex (also known as System Xc), a glutamate-cystine antiporter composed of solute carrier family 3 member 2 and solute carrier family 7 member 11 (SLC7A11), is responsible for importing cystine into cells, which is then reduced to cysteine

The mean fluorescence intensity of CellROX was significantly higher in immune cells from TLS than those from the spleen or peripheral blood (Supplemental Figure 4)