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This method is often used in clinical settings for specific health conditions, but it requires professional oversight

Frozen products can lose folate during storage due to oxidation, in contrast to canned products, which can lose more during the initial thermal treatment, but then are relatively stable because of the lack of oxygen 293

Even so, ongoing advances (such as parallelizing many microchannels in tandem) may eventually improve the throughput, enabling wider application of this technology in nutraceutical manufacturing

Additionally, ALA enhances nuclear levels of apoptosis-inducing factor and activates the caspase-dependent pathway, leading to increased cleavage of cytochrome C and PARP-1