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Therefore, mutations in the PLPBP gene disrupt this process, causing PLP to react with other substrates and impacting the metabolism of important amine or amino acid neurotransmitters in the brain, consequently leading to the development of epilepsy

Pediatric fluid and electrolyte balance: Critical care case studies

10.1016/j.intimp.2016.02.009 167

Their role in supporting elderly people in their own homes and in preventing handicap is largely undervalued -and unmeasured
