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HCV induces ER stress and alters ER calcium homeostasis, leading to oxidative stress 98

In the second phase of human experiments, we found that the mortality caused by its protective treatment was higher than that of the control group (Narayan et al., 2002)

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Carbonyl cyanide- p -trifluoromethoxyphenylhydrazone (FCCP)-stimulated respiration was lower than ADP-stimulated respiration, a pattern observed when FCCP or substrates become limiting and previously reported in Seahorse assays using isolated mitochondria 6,14